New Computer-Aided Diagnosis of Dementia Using Positron Emission Tomography: Brain Regional Sensitivity-Mapping Method

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

New Computer-Aided Diagnosis of Dementia Using Positron Emission Tomography: Brain Regional Sensitivity-Mapping Method

PURPOSE We devised a new computer-aided diagnosis method to segregate dementia using one estimated index (Total Z score) derived from the Brodmann area (BA) sensitivity map on the stereotaxic brain atlas. The purpose of this study is to investigate its accuracy to differentiate patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI) from normal adults (NL). METHODS We studie...

متن کامل

Clinical application of positron emission tomography for diagnosis of dementia.

Clinical applications of PET studies for dementia are reviewed in this paper. At the mild and moderate stages of Alzheimer's disease (AD), glucose metabolism is reduced not only in the parietotemporal region but also in the posterior cingulate and precuneus. At the advanced stage of AD, there is also a metabolic reduction in the frontal region. In AD patients, glucose metabolism is relatively p...

متن کامل

Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome.

CONTEXT Deficits in cerebral glucose utilization have been identified in patients with cognitive dysfunction attributed to various disease processes, but their prognostic and diagnostic value remains to be defined. OBJECTIVE To assess the sensitivity and specificity with which cerebral metabolic patterns at a single point in time forecast subsequent documentation of progressive dementia. DE...

متن کامل

Positron emission tomography imaging of dementia

Positron emission tomography imaging of dementia • Alzheimer's disease is prevalent and costly, but can be treated, especially in the early stages; • The current approach to dementia diagnosis involves multiple, costly assessments; • Positron emission tomography (PET) provides early positive differential diagnosis for Alzheimer's disease and other dementias; • Brain PET images show characterist...

متن کامل

Brain Mapping by Positron Emission Tomography 1 1

In this paper the basis of PET (Positron Emission Tomography) is reviewed, and it is shown that the measured signals can be modelled as the Radon transform of the desired spatial distribution of, e.g., the brain activity. Next, two of the direct reconstruction methods are presented. Both are derived from inversion of the Radon transform. It is shown that the reconstruction can be based on lteri...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: PLoS ONE

سال: 2011

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0025033